Siftome Phase 3L

GSE228393

Gene expression in cancerous and paraneoplastic tissues of patients with head and neck squamous cell carcinoma.

Not suitable Dataset does not meet the current suitability threshold.
Sample grouping CSV Contrast CSV DESeq2 metadata CSV R handoff notes Handoff report Download instructions Open GEO dataset
Source
GEO
Search intent
Patient tissue tumor-vs-normal
Intent behavior
search-intent-behavior-v1
Submission date
2023-03-28
Last update
2023-04-01
Organization
Qingdao University Affiliated Yantai Yuhuangding Hospital
Department
Department of Otorhinolaryngology, Head and Neck Surgery
Public date
2023-03-28
Experiment types
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platforms
GPL28038 DNBSEQ-G400 (Homo sapiens)
Series type
Series
SubSeries
Not available
BioProject
PRJNA949621
Supplementary files
TAR: GSE228393_RAW.tar
Organism
Homo sapiens
Assay
bulk RNA-seq
Samples
8
Study design
Tumor vs unmatched normal
Specimen/source
Tissue
Scoring version
intent-aware-scoring-v15
Ranking batch
b69568dd1e4fe1b9ee2d880bf5495d748a7e4c5c11e4107f02528c3be0e76012
Ranking created
2026-06-05T20:20:27.088676Z
Warning version
intent-aware-warnings-v2

Current Intent Interpretation

Patient tissue tumor-vs-normal

Expectations

Organism
Homo sapiens
Assay
bulk RNA-seq
Specimen/source
patient tissue or biopsy
Controls
matched normal, adjacent normal, paired normal, healthy tissue control, or otherwise normal tissue control

Rules

Default filters
Human only; Bulk RNA-seq only; Tumor-normal only; Tissue or biopsy only; Hide biofluid/model systems
Warning rules
missing or unclear control group, unclear disease context, unclear tissue source, mixed sample types, model-system markers, secondary assay context, missing processed data, or small cohort size
Score caps
non-human datasets stay below the primary recommendation band, missing colorectal/colon/rectal/CRC context stays below the primary recommendation band, biofluid and model-system datasets cannot reach Recommended by default, microarray and secondary assays are capped unless explicitly enabled, or small cohorts are capped below high-confidence recommendations
Downgraded contexts
microarray unless explicitly enabled, biofluid-only datasets, cell-line datasets, organoid datasets, xenograft or PDX datasets, non-colorectal disease contexts, or treatment-only experiments

Study Classification

Tumor vs unmatched normal Tissue

Analysis Readiness

Review before analysis
94% DE readiness

Contrast completeness

25/25 pts

Both case and control groups are present in the proposed grouping.

Minimum group size

20/20 pts

Each contrast group has at least 2 samples.

Processed data availability

20/20 pts

Processed data is marked available in the GEO index.

Sample decision clarity

15/15 pts

All samples are assigned to a case or control group.

Blocking warnings

7/10 pts

Warnings are present, but none are critical blockers.

Metadata normalization

7/10 pts

Metadata quality is usable, but still deserves review.

Blockers

  • Secondary RNA assay context should be analyzed separately from ordinary bulk RNA-seq.

Next Steps

  • Review blockers and update sample grouping or dataset selection before analysis.

Analysis Preparation Checklist

5/6 ready

Group labels reviewed

Needs review

Siftome proposed case and control labels, but no reviewer confirmation is stored yet.

Open the sample grouping CSV and confirm group labels before analysis.

Minimum sample count met

Ready

Both groups meet the minimum of 2 samples.

Confirm whether the cohort is large enough for the intended statistical analysis.

Processed counts available

Ready

Processed data availability is marked true in the GEO index.

Verify that downloaded processed files contain usable count or expression identifiers.

Ambiguous samples handled

Ready

No review-needed or unassigned samples are present in the proposed grouping.

Still scan the grouping table for biology-specific ambiguity.

Exclusion decisions recorded

Ready

No hard-excluded samples were detected by the current rules.

Record any manual exclusions in the downstream analysis notes.

Source links preserved

Ready

The dataset and sample accessions can be linked back to GEO.

Keep GEO dataset and sample links with exported metadata.

Bioinformatician Review

Bioinformatician review required

Ask a bioinformatician to review grouping, count availability, exclusions, and design before DE.

  • Analysis readiness has blockers that must be resolved before DE.
  • Assay context may require expert handling before DESeq2-style analysis.

Why This Is Ranked Here

Patient tissue tumor-vs-normal
Not suitable Dataset does not meet the current suitability threshold.

Score Components

  • relevance 50% Organism normalized. Assay type normalized.
  • comparison suitability 0% Tumor and normal sample groups detected. No excluded sample type flags detected. Tumor/normal design boosted for colorectal tumor-vs-normal tissue triage. Patient tissue or biopsy specimens boosted for tissue comparison triage. Non-colorectal cancer context downgraded for colorectal tumor-vs-normal tissue ranking.
  • metadata quality 70% Sample source clarity: All samples have source metadata and clear GSE/GSM accessions. Group clarity: Rule-based grouping found both case and control samples. Disease clarity: Disease or condition metadata was not normalized. Tissue clarity: Tissue metadata was not normalized. Treatment clarity: No unclear treatment split detected in the sample metadata. Replicate clarity: No pooled sample or technical replicate flags detected. Data availability clarity: Dataset-level processed or raw data availability is explicit.
  • data availability 100% Processed data available. Raw data available.
  • overall 34% Weighted score: 30% relevance, 30% comparison suitability, 25% metadata quality, 15% data availability. Overall score capped because comparison suitability is weak for the selected search intent. Overall score capped because fewer than ten samples limit cohort confidence. Overall score capped because tumor/normal grouping is from a non-colorectal cancer context.

Derived Classifications

  • Organism Homo sapiens Organism remains rule-derived: Homo sapiens.
  • Assay bulk RNA-seq Assay remains rule-derived: bulk RNA-seq.
  • Study design Tumor vs unmatched normal Study design remains rule-derived: Tumor vs unmatched normal.
  • Specimen/source Tissue Specimen/source remains rule-derived: Tissue.
  • Likely case group tumor sample 5 samples
  • Likely control group normal tissue 3 samples

Warnings

  • SECONDARY_ASSAY_CONTEXT warning Secondary RNA assay context such as small RNA, miRNA, circRNA, or non-coding RNA was detected.
  • DISEASE_LABEL_UNCLEAR warning Disease or condition label could not be normalized.
  • TISSUE_TYPE_MISSING warning Tissue or cell type could not be normalized.

Intent Interpretation

  • Active intent Patient tissue tumor-vs-normal Ranks human colorectal tissue or biopsy cohorts where tumor samples can be compared with normal controls.
  • Organism expectation Homo sapiens Dataset organism is interpreted as Homo sapiens.
  • Assay expectation bulk RNA-seq Dataset assay is interpreted as bulk RNA-seq.
  • Specimen assumption patient tissue or biopsy Derived specimen/source is Tissue.
  • Control-group assumption matched normal, adjacent normal, paired normal, healthy tissue control, or otherwise normal tissue control Derived study design is Tumor vs unmatched normal; likely groups are tumor sample vs normal tissue.
  • Score caps Applied when matching conditions are present non-human datasets stay below the primary recommendation band, missing colorectal/colon/rectal/CRC context stays below the primary recommendation band, biofluid and model-system datasets cannot reach Recommended by default, microarray and secondary assays are capped unless explicitly enabled, or small cohorts are capped below high-confidence recommendations
  • Warning rules 3 active warnings missing or unclear control group, unclear disease context, unclear tissue source, mixed sample types, model-system markers, secondary assay context, missing processed data, or small cohort size
  • Downgrade or exclusion reason Downgraded disease context: not a colorectal/GI cancer cohort. Derived from current-intent ranking reasons and warnings.

Applied Review Decisions

No active review decisions affect this ranking.

Ranking Facts

  • Recommendation Not suitable Dataset does not meet the current suitability threshold.
  • Supporting fact Tumor vs unmatched normal · Tissue · suitability 0%. Contributed to match or upgrade evidence.
  • Supporting fact Prioritized assay: bulk RNA-seq is the active assay expectation. Contributed to match or upgrade evidence.
  • Supporting fact Downgraded disease context: not a colorectal/GI cancer cohort. Contributed to match or upgrade evidence.
  • Supporting fact Processed data is available for downstream review. Contributed to match or upgrade evidence.
  • Supporting fact 3 warnings require review. Contributed to match or upgrade evidence.
  • Caution fact Secondary RNA assay context such as small RNA, miRNA, circRNA, or non-coding RNA was detected. Contributed to downgrade or manual-review evidence.
  • Caution fact Disease or condition label could not be normalized. Contributed to downgrade or manual-review evidence.
  • Caution fact Tissue or cell type could not be normalized. Contributed to downgrade or manual-review evidence.
  • Caution fact Non-colorectal cancer context downgraded for colorectal tumor-vs-normal tissue ranking. Contributed to downgrade or manual-review evidence.
  • Caution fact Missing or unclear metadata: Disease clarity: Disease or condition metadata was not normalized. Contributed to downgrade or manual-review evidence.
  • Caution fact Missing or unclear metadata: Tissue clarity: Tissue metadata was not normalized. Contributed to downgrade or manual-review evidence.
  • Caution fact Missing or unclear metadata: Treatment clarity: No unclear treatment split detected in the sample metadata. Contributed to downgrade or manual-review evidence.
  • Caution fact Overall score capped because comparison suitability is weak for the selected search intent. Contributed to downgrade or manual-review evidence.
  • Caution fact Overall score capped because fewer than ten samples limit cohort confidence. Contributed to downgrade or manual-review evidence.
  • Caution fact Overall score capped because tumor/normal grouping is from a non-colorectal cancer context. Contributed to downgrade or manual-review evidence.
  • Caution fact Downgraded disease context: not a colorectal/GI cancer cohort. Contributed to downgrade or manual-review evidence.
  • Caution fact Comparison suitability score is below the Phase 1 recommended threshold. Contributed to downgrade or manual-review evidence.

Manual Corrections

0 active

Source Evidence

4 sources

GEO

Primary source

Original dataset metadata, sample metadata, source links, and GEO data availability flags.

Dataset accession
GSE228393
Sample records
8 GSM samples
  • GEO has priority for original metadata under the Phase 3J source rules.
  • Processed data: available.
  • Raw data: available.
  • No external source conflict is present in the current runtime data.

recount3

Not imported

Planned trusted source for processed count availability.

GEO accession
GSE228393
  • No recount3 project identifier has been imported for this dataset.
  • Once imported, recount3 has priority for processed count availability.
  • The recount3 source filter excludes this dataset until that linkage exists.
No recount3 sync data available.

Expression Atlas

Not imported

Planned source for curated expression experiment links.

GEO accession
GSE228393
  • No Expression Atlas experiment identifier has been imported for this dataset.
  • Once imported, Expression Atlas has priority for curated expression experiment links.
  • The Expression Atlas source filter excludes this dataset until that linkage exists.
No Expression Atlas sync data available.

PubMed

Unavailable

Publication context when PubMed identifiers are already known.

GEO accession
GSE228393
  • No PubMed identifier is present in the current runtime metadata.
  • No live PubMed search is performed from the dataset detail page.
No publication identifier imported.

Dataset Feedback

0 stored

Original GEO Metadata

dataset_accession: GSE228393
dataset_title: Gene expression in cancerous and paraneoplastic tissues of patients with head and neck squamous cell carcinoma.
organism: Homo sapiens
assay_type: bulk RNA-seq
processed_data_available: true
raw_data_available: true
submission_date: 2023-03-28
last_update_date: 2023-04-01
organization_name: Qingdao University Affiliated Yantai Yuhuangding Hospital
department: Department of Otorhinolaryngology, Head and Neck Surgery
public_date: 2023-03-28
experiment_types: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
platforms: GPL28038 DNBSEQ-G400 (Homo sapiens)
sub_series: Not available
bioproject: PRJNA949621
supplementary_files: TAR: GSE228393_RAW.tar
series_type: Series

Why It Matched

  • Tumor vs unmatched normal · Tissue · suitability 0%.
  • Prioritized assay: bulk RNA-seq is the active assay expectation.
  • Downgraded disease context: not a colorectal/GI cancer cohort.
  • Processed data is available for downstream review.
  • 3 warnings require review.

Why It May Not Be Suitable

  • Secondary RNA assay context such as small RNA, miRNA, circRNA, or non-coding RNA was detected.
  • Disease or condition label could not be normalized.
  • Tissue or cell type could not be normalized.
  • Non-colorectal cancer context downgraded for colorectal tumor-vs-normal tissue ranking.
  • Missing or unclear metadata: Disease clarity: Disease or condition metadata was not normalized.
  • Missing or unclear metadata: Tissue clarity: Tissue metadata was not normalized.
  • Missing or unclear metadata: Treatment clarity: No unclear treatment split detected in the sample metadata.
  • Overall score capped because comparison suitability is weak for the selected search intent.
  • Overall score capped because fewer than ten samples limit cohort confidence.
  • Overall score capped because tumor/normal grouping is from a non-colorectal cancer context.
  • Downgraded disease context: not a colorectal/GI cancer cohort.
  • Comparison suitability score is below the Phase 1 recommended threshold.

Warnings

  • warning SECONDARY_ASSAY_CONTEXT Secondary RNA assay context such as small RNA, miRNA, circRNA, or non-coding RNA was detected.
  • warning DISEASE_LABEL_UNCLEAR Disease or condition label could not be normalized.
  • warning TISSUE_TYPE_MISSING Tissue or cell type could not be normalized.

Normalized Fields

13 fields
Field Value Source Origin Confidence Evidence Reason
assay_type bulk RNA-seq dataset GSE228393 Runtime Siftome inference GEO:dataset:GSE228393:2107fe53d74fd05fd32655407c5d8ce35ac5257640328a6d052b1e6d0225da9b high confidence bulk rna-seq dataset_accession: GSE228393 dataset_title: Gene expression in cancerous and paraneoplastic tissues of patients with head and neck squamous cell carcinoma. organism: Homo sapien... keyword match keyword match: bulk rna-seq
organism Homo sapiens dataset GSE228393 Runtime Siftome inference GEO:dataset:GSE228393:2107fe53d74fd05fd32655407c5d8ce35ac5257640328a6d052b1e6d0225da9b high confidence homo sapiens dataset_accession: GSE228393 dataset_title: Gene expression in cancerous and paraneoplastic tissues of patients with head and neck squamous cell carcinoma. organism: Homo sapien... keyword match keyword match: homo sapiens
sample_type tumor sample sample GSM7120214 Runtime Siftome inference GEO:sample:GSM7120214:522bc5afe62752469ec175e213819a000bbd4526c2ce8e70db2ee2a3918b9008 medium confidence carcinoma sample_accession: GSM7120214 sample_title: Ca_11 source_name: Hypopharyngeal carcinoma tissue characteristics: tissue: Hypopharyngeal carcinoma tissue; cell type: Squamous cell ... controlled vocabulary controlled vocabulary sample type match: carcinoma
sample_type tumor sample sample GSM7120215 Runtime Siftome inference GEO:sample:GSM7120215:2021664349aa2a5c61bae7bcf853a83b985f491bf1d89e43c001553aef04bfbe medium confidence carcinoma sample_accession: GSM7120215 sample_title: Ca_14 source_name: Hypopharyngeal carcinoma tissue characteristics: tissue: Hypopharyngeal carcinoma tissue; cell type: Squamous cell ... controlled vocabulary controlled vocabulary sample type match: carcinoma
sample_type tumor sample sample GSM7120216 Runtime Siftome inference GEO:sample:GSM7120216:1ba23993c49460c0c8417aa833ee558dc9c214b8302ad6aa7fb8f8846094370a medium confidence carcinoma sample_accession: GSM7120216 sample_title: Ca_15 source_name: Laryngeal squamous cell carcinoma tissue characteristics: tissue: Laryngeal squamous cell carcinoma tissue; cell ty... controlled vocabulary controlled vocabulary sample type match: carcinoma
sample_type tumor sample sample GSM7120217 Runtime Siftome inference GEO:sample:GSM7120217:7c47a444887c1c6ffd797fa6eccd958c3646ea1f88956a7c9b8a2607860ac82c medium confidence carcinoma sample_accession: GSM7120217 sample_title: Ca_16 source_name: Laryngeal squamous cell carcinoma tissue characteristics: tissue: Laryngeal squamous cell carcinoma tissue; cell ty... controlled vocabulary controlled vocabulary sample type match: carcinoma
sample_type tumor sample sample GSM7120218 Runtime Siftome inference GEO:sample:GSM7120218:42ebff1f974803b457bf91535e2275ed57b33da39ffc57b87b7335deec5d3453 medium confidence carcinoma sample_accession: GSM7120218 sample_title: Ca_9 source_name: Laryngeal squamous cell carcinoma tissue characteristics: tissue: Laryngeal squamous cell carcinoma tissue; cell typ... controlled vocabulary controlled vocabulary sample type match: carcinoma
sample_type normal tissue sample GSM7120219 Runtime Siftome inference GEO:sample:GSM7120219:cf3c0a928912fd3c0319fc9e4e190c7a6c38252dc18a61b5dacb7da28cd35171 low confidence normal sample_accession: GSM7120219 sample_title: Cap_15 source_name: Paraneoplastic tissue of laryngeal squamous cell carcinoma characteristics: tissue: Paraneoplastic tissue of laryn... controlled vocabulary controlled vocabulary sample type match: normal
sample_type tumor sample sample GSM7120219 Runtime Siftome inference GEO:sample:GSM7120219:cf3c0a928912fd3c0319fc9e4e190c7a6c38252dc18a61b5dacb7da28cd35171 medium confidence carcinoma sample_accession: GSM7120219 sample_title: Cap_15 source_name: Paraneoplastic tissue of laryngeal squamous cell carcinoma characteristics: tissue: Paraneoplastic tissue of laryn... controlled vocabulary controlled vocabulary sample type match: carcinoma
sample_type normal tissue sample GSM7120220 Runtime Siftome inference GEO:sample:GSM7120220:f2d8bec7cfe8ce9c43d3a2d3e62952c66cfdfee448072e1a42c8b6b735cdca89 low confidence normal sample_accession: GSM7120220 sample_title: Cap_16 source_name: Paraneoplastic tissue of laryngeal squamous cell carcinoma characteristics: tissue: Paraneoplastic tissue of laryn... controlled vocabulary controlled vocabulary sample type match: normal
sample_type tumor sample sample GSM7120220 Runtime Siftome inference GEO:sample:GSM7120220:f2d8bec7cfe8ce9c43d3a2d3e62952c66cfdfee448072e1a42c8b6b735cdca89 medium confidence carcinoma sample_accession: GSM7120220 sample_title: Cap_16 source_name: Paraneoplastic tissue of laryngeal squamous cell carcinoma characteristics: tissue: Paraneoplastic tissue of laryn... controlled vocabulary controlled vocabulary sample type match: carcinoma
sample_type normal tissue sample GSM7120221 Runtime Siftome inference GEO:sample:GSM7120221:0078f03ae4063faac322a5b1de136fb344cce95a0b116bf5423f7be9f3e028b9 low confidence normal sample_accession: GSM7120221 sample_title: Cap_9 source_name: Paraneoplastic tissue of laryngeal squamous cell carcinoma characteristics: tissue: Paraneoplastic tissue of laryng... controlled vocabulary controlled vocabulary sample type match: normal
sample_type tumor sample sample GSM7120221 Runtime Siftome inference GEO:sample:GSM7120221:0078f03ae4063faac322a5b1de136fb344cce95a0b116bf5423f7be9f3e028b9 medium confidence carcinoma sample_accession: GSM7120221 sample_title: Cap_9 source_name: Paraneoplastic tissue of laryngeal squamous cell carcinoma characteristics: tissue: Paraneoplastic tissue of laryng... controlled vocabulary controlled vocabulary sample type match: carcinoma

Sample Group Preview

Possible case samples

Samples currently treated as the comparison case group.

5
  • GSM7120214 Ca_11 tumor sample Case marker detected. Hypopharyngeal carcinoma tissue tissue: Hypopharyngeal carcinoma tissue; cell type: Squamous cell carcinoma
  • GSM7120215 Ca_14 tumor sample Case marker detected. Hypopharyngeal carcinoma tissue tissue: Hypopharyngeal carcinoma tissue; cell type: Squamous cell carcinoma
  • GSM7120216 Ca_15 tumor sample Case marker detected. Laryngeal squamous cell carcinoma tissue tissue: Laryngeal squamous cell carcinoma tissue; cell type: Squamous cell carcinoma
  • GSM7120217 Ca_16 tumor sample Case marker detected. Laryngeal squamous cell carcinoma tissue tissue: Laryngeal squamous cell carcinoma tissue; cell type: Squamous cell carcinoma
  • GSM7120218 Ca_9 tumor sample Case marker detected. Laryngeal squamous cell carcinoma tissue tissue: Laryngeal squamous cell carcinoma tissue; cell type: Squamous cell carcinoma

Possible control samples

Samples currently treated as controls or baseline.

3
  • GSM7120219 Cap_15 normal tissue Control marker detected. Paraneoplastic tissue of laryngeal squamous cell carcinoma tissue: Paraneoplastic tissue of laryngeal squamous cell carcinoma; cell type: Normal human epithelial tissue
  • GSM7120220 Cap_16 normal tissue Control marker detected. Paraneoplastic tissue of laryngeal squamous cell carcinoma tissue: Paraneoplastic tissue of laryngeal squamous cell carcinoma; cell type: Normal human epithelial tissue
  • GSM7120221 Cap_9 normal tissue Control marker detected. Paraneoplastic tissue of laryngeal squamous cell carcinoma tissue: Paraneoplastic tissue of laryngeal squamous cell carcinoma; cell type: Normal human epithelial tissue

Unassigned samples

Samples with no explicit case or control marker.

0

No samples

Excluded samples

Samples excluded from grouping by hard exclusion rules.

0

No samples

Ambiguous samples

Samples that need manual review before trusting grouping.

0

No samples

Metadata Quality Components

Persisted metadata quality

70 pts
Clarity
70%
Weight
100 pts

Sample source clarity: All samples have source metadata and clear GSE/GSM accessions. Group clarity: Rule-based grouping found both case and control samples. Disease clarity: Disease or condition metadata was not normalized. Tissue clarity: Tissue metadata was not normalized. Treatment clarity: No unclear treatment split detected in the sample metadata. Replicate clarity: No pooled sample or technical replicate flags detected. Data availability clarity: Dataset-level processed or raw data availability is explicit.

Detected Sample Groups

tumor sample

5 samples
  • GSM7120214 Ca_11 Hypopharyngeal carcinoma tissue tissue: Hypopharyngeal carcinoma tissue; cell type: Squamous cell carcinoma
  • GSM7120215 Ca_14 Hypopharyngeal carcinoma tissue tissue: Hypopharyngeal carcinoma tissue; cell type: Squamous cell carcinoma
  • GSM7120216 Ca_15 Laryngeal squamous cell carcinoma tissue tissue: Laryngeal squamous cell carcinoma tissue; cell type: Squamous cell carcinoma
  • GSM7120217 Ca_16 Laryngeal squamous cell carcinoma tissue tissue: Laryngeal squamous cell carcinoma tissue; cell type: Squamous cell carcinoma
  • GSM7120218 Ca_9 Laryngeal squamous cell carcinoma tissue tissue: Laryngeal squamous cell carcinoma tissue; cell type: Squamous cell carcinoma

normal tissue

3 samples
  • GSM7120219 Cap_15 Paraneoplastic tissue of laryngeal squamous cell carcinoma tissue: Paraneoplastic tissue of laryngeal squamous cell carcinoma; cell type: Normal human epithelial tissue
  • GSM7120220 Cap_16 Paraneoplastic tissue of laryngeal squamous cell carcinoma tissue: Paraneoplastic tissue of laryngeal squamous cell carcinoma; cell type: Normal human epithelial tissue
  • GSM7120221 Cap_9 Paraneoplastic tissue of laryngeal squamous cell carcinoma tissue: Paraneoplastic tissue of laryngeal squamous cell carcinoma; cell type: Normal human epithelial tissue

Score Breakdown

50%

relevance

  • Organism normalized.
  • Assay type normalized.
0%

comparison suitability

  • Tumor and normal sample groups detected.
  • No excluded sample type flags detected.
  • Tumor/normal design boosted for colorectal tumor-vs-normal tissue triage.
  • Patient tissue or biopsy specimens boosted for tissue comparison triage.
  • Non-colorectal cancer context downgraded for colorectal tumor-vs-normal tissue ranking.
70%

metadata quality

  • Sample source clarity: All samples have source metadata and clear GSE/GSM accessions.
  • Group clarity: Rule-based grouping found both case and control samples.
  • Disease clarity: Disease or condition metadata was not normalized.
  • Tissue clarity: Tissue metadata was not normalized.
  • Treatment clarity: No unclear treatment split detected in the sample metadata.
  • Replicate clarity: No pooled sample or technical replicate flags detected.
  • Data availability clarity: Dataset-level processed or raw data availability is explicit.
100%

data availability

  • Processed data available.
  • Raw data available.
34%

overall

  • Weighted score: 30% relevance, 30% comparison suitability, 25% metadata quality, 15% data availability.
  • Overall score capped because comparison suitability is weak for the selected search intent.
  • Overall score capped because fewer than ten samples limit cohort confidence.
  • Overall score capped because tumor/normal grouping is from a non-colorectal cancer context.

Sample Links

8 samples

Review Audit Trail

0 decisions

No review decisions have been stored for this dataset.