Expectations
- Organism
- Homo sapiens
- Assay
- bulk RNA-seq
- Specimen/source
- patient tissue or biopsy
- Controls
- matched normal, adjacent normal, paired normal, healthy tissue control, or otherwise normal tissue control
Siftome Phase 3L
GSE306117Both case and control groups are present in the proposed grouping.
Each contrast group has at least 2 samples.
Processed data is marked available in the GEO index.
Unassigned or review-needed samples remain before analysis.
No dataset warnings are present.
Metadata quality is high enough to support downstream handoff.
Siftome proposed case and control labels, but no reviewer confirmation is stored yet.
Open the sample grouping CSV and confirm group labels before analysis.Both groups meet the minimum of 2 samples.
Confirm whether the cohort is large enough for the intended statistical analysis.Processed data availability is marked true in the GEO index.
Verify that downloaded processed files contain usable count or expression identifiers.0 review-needed samples and 5 unassigned samples remain.
Resolve ambiguous and unassigned samples before finalizing the contrast.No hard-excluded samples were detected by the current rules.
Record any manual exclusions in the downstream analysis notes.The dataset and sample accessions can be linked back to GEO.
Keep GEO dataset and sample links with exported metadata.Ask a bioinformatician to review grouping, count availability, exclusions, and design before DE.
No ranking warnings are active.
No active review decisions affect this ranking.
No active manual corrections are applied to this dataset.
Homo sapiens
dataset_accession: GSE306117 organism: Homo sapiens dataset_title: Distinct genomic and immunologic tumor evolution in germline TP53-driven breast cancers
bulk RNA-seq
assay_type: bulk RNA-seq experiment_types: Expression profiling by high throughput sequencing platforms: GPL34281 Illumina NovaSeq X (Homo sapiens) dataset_title: Distinct genomic and immunologic tumor evolution in germline TP53-driven breast cancers
Tumor vs unmatched normal
dataset_title: Distinct genomic and immunologic tumor evolution in germline TP53-driven breast cancers experiment_types: Expression profiling by high throughput sequencing sample_context: GSM9193483: source_name=Breast Tumor; characteristics=tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples GSM9193484: source_name=Control Breast Tissue; characteristics=tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples GSM9193485: source_name=Breast Tumor; characteristics=tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples GSM9193486: source_name=Control Breast Tissue; characteristics=tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples GSM9193487: source_name=Breast Tumor; characteristics=tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples GSM9193488: source_name=Control Breast Tissue; characteristics=tissue: Control Breast [Correction source preview truncated.]
Tissue
dataset_title: Distinct genomic and immunologic tumor evolution in germline TP53-driven breast cancers sample_context: GSM9193483: source_name=Breast Tumor; characteristics=tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples GSM9193484: source_name=Control Breast Tissue; characteristics=tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples GSM9193485: source_name=Breast Tumor; characteristics=tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples GSM9193486: source_name=Control Breast Tissue; characteristics=tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples GSM9193487: source_name=Breast Tumor; characteristics=tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples GSM9193488: source_name=Control Breast Tissue; characteristics=tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
breast cancer
dataset_title: Distinct genomic and immunologic tumor evolution in germline TP53-driven breast cancers sample_context: GSM9193483: source_name=Breast Tumor; characteristics=tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples GSM9193484: source_name=Control Breast Tissue; characteristics=tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples GSM9193485: source_name=Breast Tumor; characteristics=tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples GSM9193486: source_name=Control Breast Tissue; characteristics=tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples GSM9193487: source_name=Breast Tumor; characteristics=tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples GSM9193488: source_name=Control Breast Tissue; characteristics=tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Eligible for Patient tissue tumor-vs-normal as Not suitable
dataset_accession: GSE306117 dataset_title: Distinct genomic and immunologic tumor evolution in germline TP53-driven breast cancers organism: Homo sapiens assay_type: bulk RNA-seq sample_context: GSM9193483: source_name=Breast Tumor; characteristics=tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples GSM9193484: source_name=Control Breast Tissue; characteristics=tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples GSM9193485: source_name=Breast Tumor; characteristics=tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples GSM9193486: source_name=Control Breast Tissue; characteristics=tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples GSM9193487: source_name=Breast Tumor; characteristics=tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples GSM9193488: source_name=Control Breast Tissue; characteristics=tissue: Control [Correction source preview truncated.]
Eligible for Patient tissue tumor-vs-normal as Not suitable
dataset_accession: GSE306117 dataset_title: Distinct genomic and immunologic tumor evolution in germline TP53-driven breast cancers organism: Homo sapiens assay_type: bulk RNA-seq sample_context: GSM9193483: source_name=Breast Tumor; characteristics=tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples GSM9193484: source_name=Control Breast Tissue; characteristics=tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples GSM9193485: source_name=Breast Tumor; characteristics=tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples GSM9193486: source_name=Control Breast Tissue; characteristics=tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples GSM9193487: source_name=Breast Tumor; characteristics=tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples GSM9193488: source_name=Control Breast Tissue; characteristics=tissue: Control [Correction source preview truncated.]
tumor sample (case)
sample_accession: GSM9193483 sample_title: 103-B27-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193483 sample_title: 103-B27-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193484 sample_title: 103-B36-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193484 sample_title: 103-B36-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193485 sample_title: 106-3B-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193485 sample_title: 106-3B-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193486 sample_title: 106-3L-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193486 sample_title: 106-3L-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193487 sample_title: 108-3N-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193487 sample_title: 108-3N-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193488 sample_title: 108-3T-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193488 sample_title: 108-3T-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193489 sample_title: 120-3C-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193489 sample_title: 120-3C-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193490 sample_title: 120-3S-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193490 sample_title: 120-3S-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193491 sample_title: 125-3I-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193491 sample_title: 125-3I-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193492 sample_title: 125-3O-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193492 sample_title: 125-3O-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193493 sample_title: 126-B1-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193493 sample_title: 126-B1-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193494 sample_title: 126-B4-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193494 sample_title: 126-B4-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193495 sample_title: 126-B7-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP54; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193495 sample_title: 126-B7-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP54; batch: LFS Samples
unassigned (unassigned)
sample_accession: GSM9193496 sample_title: 126-D2-contralateral source_name: Contralateral Breast Tissue characteristics: tissue: Contralateral Breast Tissue; genotype: Mutant TP55; batch: LFS Samples
Included in derived sample grouping as unassigned
sample_accession: GSM9193496 sample_title: 126-D2-contralateral source_name: Contralateral Breast Tissue characteristics: tissue: Contralateral Breast Tissue; genotype: Mutant TP55; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193497 sample_title: 128-2O-surrounding_R source_name: Tissue Surrounding Breast Tumor characteristics: tissue: Tissue Surrounding Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193497 sample_title: 128-2O-surrounding_R source_name: Tissue Surrounding Breast Tumor characteristics: tissue: Tissue Surrounding Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193498 sample_title: 128-2C-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193498 sample_title: 128-2C-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193499 sample_title: 130-1L-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193499 sample_title: 130-1L-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193500 sample_title: 130-1O-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193500 sample_title: 130-1O-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193501 sample_title: 152-2F-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193501 sample_title: 152-2F-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193502 sample_title: 152-NA-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193502 sample_title: 152-NA-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193503 sample_title: 157-1M-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193503 sample_title: 157-1M-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193504 sample_title: 157-1V-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193504 sample_title: 157-1V-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193505 sample_title: 160-3C-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193505 sample_title: 160-3C-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193506 sample_title: 160-3L-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193506 sample_title: 160-3L-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193507 sample_title: 169-5H-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193507 sample_title: 169-5H-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193508 sample_title: 169-5I-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193508 sample_title: 169-5I-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193509 sample_title: 177-3C-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193509 sample_title: 177-3C-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193510 sample_title: 177-3H-Tumor source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193510 sample_title: 177-3H-Tumor source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193511 sample_title: 177-3K-Normal source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193511 sample_title: 177-3K-Normal source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193512 sample_title: 180-5C-Tumor source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193512 sample_title: 180-5C-Tumor source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193513 sample_title: 180-5J-Normal source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193513 sample_title: 180-5J-Normal source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193514 sample_title: 186-6C-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193514 sample_title: 186-6C-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193515 sample_title: 186-6Z-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193515 sample_title: 186-6Z-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193516 sample_title: 187-1H-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193516 sample_title: 187-1H-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193517 sample_title: 187-3C-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193517 sample_title: 187-3C-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193518 sample_title: 193-3F-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193518 sample_title: 193-3F-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193519 sample_title: 193-3H-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193519 sample_title: 193-3H-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193520 sample_title: 196-2EE-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193520 sample_title: 196-2EE-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193521 sample_title: 196-2M-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193521 sample_title: 196-2M-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193522 sample_title: 197-2B-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193522 sample_title: 197-2B-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193523 sample_title: 197-2O-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193523 sample_title: 197-2O-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
unassigned (unassigned)
sample_accession: GSM9193524 sample_title: 24-A6-contralateral source_name: Contralateral Breast Tissue characteristics: tissue: Contralateral Breast Tissue; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as unassigned
sample_accession: GSM9193524 sample_title: 24-A6-contralateral source_name: Contralateral Breast Tissue characteristics: tissue: Contralateral Breast Tissue; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193525 sample_title: 24-C8-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193525 sample_title: 24-C8-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193526 sample_title: 27-C-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193526 sample_title: 27-C-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
normal tissue (control)
sample_accession: GSM9193527 sample_title: 33-C3-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193527 sample_title: 33-C3-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193528 sample_title: 33-C4-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193528 sample_title: 33-C4-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193529 sample_title: 35-B18-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193529 sample_title: 35-B18-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193530 sample_title: 35-B4-surrounding_R source_name: Tissue Surrounding Breast Tumor characteristics: tissue: Tissue Surrounding Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193530 sample_title: 35-B4-surrounding_R source_name: Tissue Surrounding Breast Tumor characteristics: tissue: Tissue Surrounding Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193531 sample_title: 35-C7-surrounding_L source_name: Tissue Surrounding Breast Tumor characteristics: tissue: Tissue Surrounding Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193531 sample_title: 35-C7-surrounding_L source_name: Tissue Surrounding Breast Tumor characteristics: tissue: Tissue Surrounding Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193532 sample_title: 42-B2-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193532 sample_title: 42-B2-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193533 sample_title: 45-2-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193533 sample_title: 45-2-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193534 sample_title: 46-D3-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193534 sample_title: 46-D3-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193535 sample_title: 50-1I-surrounding_R source_name: Tissue Surrounding Breast Tumor characteristics: tissue: Tissue Surrounding Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193535 sample_title: 50-1I-surrounding_R source_name: Tissue Surrounding Breast Tumor characteristics: tissue: Tissue Surrounding Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193536 sample_title: 50-1O-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193536 sample_title: 50-1O-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193537 sample_title: 50-2D-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193537 sample_title: 50-2D-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193538 sample_title: 53-1M-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193538 sample_title: 53-1M-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193539 sample_title: 57-2E-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193539 sample_title: 57-2E-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193540 sample_title: 58-2E-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193540 sample_title: 58-2E-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193541 sample_title: 58-2I-surrounding source_name: Tissue Surrounding Breast Tumor characteristics: tissue: Tissue Surrounding Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193541 sample_title: 58-2I-surrounding source_name: Tissue Surrounding Breast Tumor characteristics: tissue: Tissue Surrounding Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
unassigned (unassigned)
sample_accession: GSM9193542 sample_title: 58-8E-contralateral source_name: Contralateral Breast Tissue characteristics: tissue: Contralateral Breast Tissue; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as unassigned
sample_accession: GSM9193542 sample_title: 58-8E-contralateral source_name: Contralateral Breast Tissue characteristics: tissue: Contralateral Breast Tissue; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193543 sample_title: 72-A1-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193543 sample_title: 72-A1-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193544 sample_title: 75-1C-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193544 sample_title: 75-1C-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193545 sample_title: 75-1J-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193545 sample_title: 75-1J-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193546 sample_title: 84-A12-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193546 sample_title: 84-A12-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
unassigned (unassigned)
sample_accession: GSM9193547 sample_title: 84-C16-contralateral source_name: Contralateral Breast Tissue characteristics: tissue: Contralateral Breast Tissue; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as unassigned
sample_accession: GSM9193547 sample_title: 84-C16-contralateral source_name: Contralateral Breast Tissue characteristics: tissue: Contralateral Breast Tissue; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193548 sample_title: 85-1E-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193548 sample_title: 85-1E-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193549 sample_title: 85-1Y-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193549 sample_title: 85-1Y-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
unassigned (unassigned)
sample_accession: GSM9193550 sample_title: 88-B6-contralateral source_name: Contralateral Breast Tissue characteristics: tissue: Contralateral Breast Tissue; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as unassigned
sample_accession: GSM9193550 sample_title: 88-B6-contralateral source_name: Contralateral Breast Tissue characteristics: tissue: Contralateral Breast Tissue; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193551 sample_title: 88-D15-surrounding source_name: Tissue Surrounding Breast Tumor characteristics: tissue: Tissue Surrounding Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193551 sample_title: 88-D15-surrounding source_name: Tissue Surrounding Breast Tumor characteristics: tissue: Tissue Surrounding Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193552 sample_title: 88-D6-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193552 sample_title: 88-D6-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: Mutant TP53; batch: LFS Samples
tumor sample (case)
sample_accession: GSM9193553 sample_title: 9-6H-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193553 sample_title: 9-6H-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193554 sample_title: 9-6I-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193554 sample_title: 9-6I-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
tumor sample (case)
sample_accession: GSM9193555 sample_title: 95-B4-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as tumor sample
sample_accession: GSM9193555 sample_title: 95-B4-Tumor source_name: Breast Tumor characteristics: tissue: Breast Tumor; genotype: WT TP53; batch: Non LFS Samples
normal tissue (control)
sample_accession: GSM9193556 sample_title: 95-D3-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Included in derived sample grouping as normal tissue
sample_accession: GSM9193556 sample_title: 95-D3-Normal source_name: Control Breast Tissue characteristics: tissue: Control Breast Tissue; genotype: WT TP53; batch: Non LFS Samples
Original dataset metadata, sample metadata, source links, and GEO data availability flags.
Planned trusted source for processed count availability.
Planned source for curated expression experiment links.
Publication context when PubMed identifiers are already known.
No project feedback stored for this dataset.
dataset_accession: GSE306117 dataset_title: Distinct genomic and immunologic tumor evolution in germline TP53-driven breast cancers organism: Homo sapiens assay_type: bulk RNA-seq processed_data_available: true raw_data_available: true submission_date: 2025-08-21 last_update_date: 2026-01-01 organization_name: University of Pennsylvania department: Not available public_date: 2026-01-01 experiment_types: Expression profiling by high throughput sequencing platforms: GPL34281 Illumina NovaSeq X (Homo sapiens) sub_series: Not available bioproject: PRJNA1309161 supplementary_files: TAR: GSE306117_RAW.tar series_type: Series
No warnings
Samples currently treated as the comparison case group.
Samples currently treated as controls or baseline.
Samples with no explicit case or control marker.
Samples excluded from grouping by hard exclusion rules.
No samples
Samples that need manual review before trusting grouping.
No samples
No review decisions have been stored for this dataset.