Expectations
- Organism
- Homo sapiens
- Assay
- bulk RNA-seq
- Specimen/source
- patient tissue or biopsy
- Controls
- matched normal, adjacent normal, paired normal, healthy tissue control, or otherwise normal tissue control
Both case and control groups are present in the proposed grouping.
A contrast exists, but at least one group is below the minimum sample count.
Processed data is marked available in the GEO index.
All samples are assigned to a case or control group.
No dataset warnings are present.
Metadata quality is high enough to support downstream handoff.
Siftome proposed case and control labels, but no reviewer confirmation is stored yet.
Open the sample grouping CSV and confirm group labels before analysis.At least one group has fewer than 2 samples.
Choose a larger dataset or merge only scientifically valid groups.Processed data availability is marked true in the GEO index.
Verify that downloaded processed files contain usable count or expression identifiers.No review-needed or unassigned samples are present in the proposed grouping.
Still scan the grouping table for biology-specific ambiguity.No hard-excluded samples were detected by the current rules.
Record any manual exclusions in the downstream analysis notes.The dataset and sample accessions can be linked back to GEO.
Keep GEO dataset and sample links with exported metadata.Ask a bioinformatician to review grouping, count availability, exclusions, and design before DE.
No ranking warnings are active.
No active review decisions affect this ranking.
No active manual corrections are applied to this dataset.
Homo sapiens
dataset_accession: GSE92914 organism: Homo sapiens dataset_title: RNA-Seq analysis of human colorectal cancer with liver metastasis
bulk RNA-seq
assay_type: bulk RNA-seq experiment_types: Expression profiling by high throughput sequencing platforms: GPL18573 Illumina NextSeq 500 (Homo sapiens) dataset_title: RNA-Seq analysis of human colorectal cancer with liver metastasis
Tumor vs matched normal
dataset_title: RNA-Seq analysis of human colorectal cancer with liver metastasis experiment_types: Expression profiling by high throughput sequencing sample_context: GSM2440320: source_name=liver; characteristics=gender: female; age (yr): 62; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient GSM2440321: source_name=right colon; characteristics=gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient GSM2440322: source_name=right colon; characteristics=gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon adjacent normal; disease state: colorectal cancer patient GSM2440323: source_name=liver; characteristics=gender: male; age (yr): 58; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient GSM2440324: source_name=right colon; characteristics=gender: [Correction source preview truncated.]
Tissue
dataset_title: RNA-Seq analysis of human colorectal cancer with liver metastasis sample_context: GSM2440320: source_name=liver; characteristics=gender: female; age (yr): 62; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient GSM2440321: source_name=right colon; characteristics=gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient GSM2440322: source_name=right colon; characteristics=gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon adjacent normal; disease state: colorectal cancer patient GSM2440323: source_name=liver; characteristics=gender: male; age (yr): 58; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient GSM2440324: source_name=right colon; characteristics=gender: male; age (yr): 58; staging: T3N2M1; tissue: right colon primary tum [Correction source preview truncated.]
colorectal cancer
dataset_title: RNA-Seq analysis of human colorectal cancer with liver metastasis sample_context: GSM2440320: source_name=liver; characteristics=gender: female; age (yr): 62; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient GSM2440321: source_name=right colon; characteristics=gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient GSM2440322: source_name=right colon; characteristics=gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon adjacent normal; disease state: colorectal cancer patient GSM2440323: source_name=liver; characteristics=gender: male; age (yr): 58; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient GSM2440324: source_name=right colon; characteristics=gender: male; age (yr): 58; staging: T3N2M1; tissue: right colon primary tum [Correction source preview truncated.]
Eligible for Patient tissue tumor-vs-normal as Recommended
dataset_accession: GSE92914 dataset_title: RNA-Seq analysis of human colorectal cancer with liver metastasis organism: Homo sapiens assay_type: bulk RNA-seq sample_context: GSM2440320: source_name=liver; characteristics=gender: female; age (yr): 62; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient GSM2440321: source_name=right colon; characteristics=gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient GSM2440322: source_name=right colon; characteristics=gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon adjacent normal; disease state: colorectal cancer patient GSM2440323: source_name=liver; characteristics=gender: male; age (yr): 58; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient GSM2440324: source_name=right colon; characteristics= [Correction source preview truncated.]
Eligible for Patient tissue tumor-vs-normal as Recommended
dataset_accession: GSE92914 dataset_title: RNA-Seq analysis of human colorectal cancer with liver metastasis organism: Homo sapiens assay_type: bulk RNA-seq sample_context: GSM2440320: source_name=liver; characteristics=gender: female; age (yr): 62; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient GSM2440321: source_name=right colon; characteristics=gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient GSM2440322: source_name=right colon; characteristics=gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon adjacent normal; disease state: colorectal cancer patient GSM2440323: source_name=liver; characteristics=gender: male; age (yr): 58; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient GSM2440324: source_name=right colon; characteristics= [Correction source preview truncated.]
tumor sample (case)
sample_accession: GSM2440320 sample_title: liver metastasis 1_LM source_name: liver characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient
Included in derived sample grouping as tumor sample
sample_accession: GSM2440320 sample_title: liver metastasis 1_LM source_name: liver characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient
tumor sample (case)
sample_accession: GSM2440321 sample_title: right colon primary tumor 1_MT source_name: right colon characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
Included in derived sample grouping as tumor sample
sample_accession: GSM2440321 sample_title: right colon primary tumor 1_MT source_name: right colon characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
normal tissue (control)
sample_accession: GSM2440322 sample_title: right colon adjacent normal 1_PN source_name: right colon characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon adjacent normal; disease state: colorectal cancer patient
Included in derived sample grouping as normal tissue
sample_accession: GSM2440322 sample_title: right colon adjacent normal 1_PN source_name: right colon characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon adjacent normal; disease state: colorectal cancer patient
tumor sample (case)
sample_accession: GSM2440323 sample_title: liver metastasis 2_LM source_name: liver characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient
Included in derived sample grouping as tumor sample
sample_accession: GSM2440323 sample_title: liver metastasis 2_LM source_name: liver characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient
tumor sample (case)
sample_accession: GSM2440324 sample_title: right colon primary tumor 2_MT source_name: right colon characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
Included in derived sample grouping as tumor sample
sample_accession: GSM2440324 sample_title: right colon primary tumor 2_MT source_name: right colon characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
tumor sample (case)
sample_accession: GSM2440325 sample_title: right colon primary tumor 2_PN source_name: right colon characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
Included in derived sample grouping as tumor sample
sample_accession: GSM2440325 sample_title: right colon primary tumor 2_PN source_name: right colon characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
tumor sample (case)
sample_accession: GSM2440326 sample_title: liver metastasis 3_LM source_name: liver characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: liver metastasis; disease state: colorectal cancer patient
Included in derived sample grouping as tumor sample
sample_accession: GSM2440326 sample_title: liver metastasis 3_LM source_name: liver characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: liver metastasis; disease state: colorectal cancer patient
tumor sample (case)
sample_accession: GSM2440327 sample_title: right colon primary tumor 3_MT source_name: right colon characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
Included in derived sample grouping as tumor sample
sample_accession: GSM2440327 sample_title: right colon primary tumor 3_MT source_name: right colon characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
tumor sample (case)
sample_accession: GSM2440328 sample_title: right colon primary tumor 3_PN source_name: right colon characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
Included in derived sample grouping as tumor sample
sample_accession: GSM2440328 sample_title: right colon primary tumor 3_PN source_name: right colon characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
tumor sample (case)
sample_accession: GSM2440329 sample_title: right colon primary tumor 4_NM source_name: right colon characteristics: gender: male; age (yr): 66; staging: T3N0M0; tissue: right colon primary tumor; disease state: colorectal cancer patient
Included in derived sample grouping as tumor sample
sample_accession: GSM2440329 sample_title: right colon primary tumor 4_NM source_name: right colon characteristics: gender: male; age (yr): 66; staging: T3N0M0; tissue: right colon primary tumor; disease state: colorectal cancer patient
tumor sample (case)
sample_accession: GSM2440330 sample_title: right colon primary tumor 5_NM source_name: right colon characteristics: gender: male; age (yr): 62; staging: T3N0M0; tissue: right colon primary tumor; disease state: colorectal cancer patient
Included in derived sample grouping as tumor sample
sample_accession: GSM2440330 sample_title: right colon primary tumor 5_NM source_name: right colon characteristics: gender: male; age (yr): 62; staging: T3N0M0; tissue: right colon primary tumor; disease state: colorectal cancer patient
tumor sample (case)
sample_accession: GSM2440331 sample_title: right colon primary tumor 6_NM source_name: right colon characteristics: gender: male; age (yr): 72; staging: T3N0M0; tissue: right colon primary tumor; disease state: colorectal cancer patient
Included in derived sample grouping as tumor sample
sample_accession: GSM2440331 sample_title: right colon primary tumor 6_NM source_name: right colon characteristics: gender: male; age (yr): 72; staging: T3N0M0; tissue: right colon primary tumor; disease state: colorectal cancer patient
Original dataset metadata, sample metadata, source links, and GEO data availability flags.
Planned trusted source for processed count availability.
Planned source for curated expression experiment links.
Publication context when PubMed identifiers are already known.
No project feedback stored for this dataset.
dataset_accession: GSE92914 dataset_title: RNA-Seq analysis of human colorectal cancer with liver metastasis organism: Homo sapiens assay_type: bulk RNA-seq processed_data_available: true raw_data_available: true submission_date: 2016-12-26 last_update_date: 2019-05-15 organization_name: Shanghai Tenth People's Hospital department: Not available public_date: 2018-12-25 experiment_types: Expression profiling by high throughput sequencing platforms: GPL18573 Illumina NextSeq 500 (Homo sapiens) sub_series: Not available bioproject: PRJNA358825 supplementary_files: TAR: GSE92914_RAW.tar series_type: Series
No warnings
Samples currently treated as the comparison case group.
Samples currently treated as controls or baseline.
Samples with no explicit case or control marker.
No samples
Samples excluded from grouping by hard exclusion rules.
No samples
Samples that need manual review before trusting grouping.
No samples
No review decisions have been stored for this dataset.