Siftome Phase 3L

GSE92914

RNA-Seq analysis of human colorectal cancer with liver metastasis

Source
GEO
Search intent
Patient tissue tumor-vs-normal
Intent behavior
search-intent-behavior-v1
Submission date
2016-12-26
Last update
2019-05-15
Organization
Shanghai Tenth People's Hospital
Department
Not available
Public date
2018-12-25
Experiment types
Expression profiling by high throughput sequencing
Platforms
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Series type
Series
SubSeries
Not available
BioProject
PRJNA358825
Supplementary files
TAR: GSE92914_RAW.tar
Organism
Homo sapiens
Assay
bulk RNA-seq
Samples
12
Study design
Tumor vs matched normal
Specimen/source
Tissue
Scoring version
intent-aware-scoring-v15
Ranking batch
b69568dd1e4fe1b9ee2d880bf5495d748a7e4c5c11e4107f02528c3be0e76012
Ranking created
2026-06-05T20:20:27.088676Z
Warning version
intent-aware-warnings-v2

Current Intent Interpretation

Patient tissue tumor-vs-normal

Expectations

Organism
Homo sapiens
Assay
bulk RNA-seq
Specimen/source
patient tissue or biopsy
Controls
matched normal, adjacent normal, paired normal, healthy tissue control, or otherwise normal tissue control

Rules

Default filters
Human only; Bulk RNA-seq only; Tumor-normal only; Tissue or biopsy only; Hide biofluid/model systems
Warning rules
missing or unclear control group, unclear disease context, unclear tissue source, mixed sample types, model-system markers, secondary assay context, missing processed data, or small cohort size
Score caps
non-human datasets stay below the primary recommendation band, missing colorectal/colon/rectal/CRC context stays below the primary recommendation band, biofluid and model-system datasets cannot reach Recommended by default, microarray and secondary assays are capped unless explicitly enabled, or small cohorts are capped below high-confidence recommendations
Downgraded contexts
microarray unless explicitly enabled, biofluid-only datasets, cell-line datasets, organoid datasets, xenograft or PDX datasets, non-colorectal disease contexts, or treatment-only experiments

Study Classification

Tumor vs matched normal Tissue

Analysis Readiness

Review before analysis
88% DE readiness

Contrast completeness

25/25 pts

Both case and control groups are present in the proposed grouping.

Minimum group size

8/20 pts

A contrast exists, but at least one group is below the minimum sample count.

Processed data availability

20/20 pts

Processed data is marked available in the GEO index.

Sample decision clarity

15/15 pts

All samples are assigned to a case or control group.

Blocking warnings

10/10 pts

No dataset warnings are present.

Metadata normalization

10/10 pts

Metadata quality is high enough to support downstream handoff.

Blockers

  • At least one contrast group is below the minimum sample count.

Next Steps

  • Review blockers and update sample grouping or dataset selection before analysis.

Analysis Preparation Checklist

4/6 ready

Group labels reviewed

Needs review

Siftome proposed case and control labels, but no reviewer confirmation is stored yet.

Open the sample grouping CSV and confirm group labels before analysis.

Minimum sample count met

Blocked

At least one group has fewer than 2 samples.

Choose a larger dataset or merge only scientifically valid groups.

Processed counts available

Ready

Processed data availability is marked true in the GEO index.

Verify that downloaded processed files contain usable count or expression identifiers.

Ambiguous samples handled

Ready

No review-needed or unassigned samples are present in the proposed grouping.

Still scan the grouping table for biology-specific ambiguity.

Exclusion decisions recorded

Ready

No hard-excluded samples were detected by the current rules.

Record any manual exclusions in the downstream analysis notes.

Source links preserved

Ready

The dataset and sample accessions can be linked back to GEO.

Keep GEO dataset and sample links with exported metadata.

Bioinformatician Review

Bioinformatician review required

Ask a bioinformatician to review grouping, count availability, exclusions, and design before DE.

  • Analysis readiness has blockers that must be resolved before DE.
  • Analysis preparation checklist contains blocked items.
  • At least one comparison group has fewer than two samples.

Why This Is Ranked Here

Patient tissue tumor-vs-normal
Recommended Scores and metadata are strong enough for direct review.

Score Components

  • relevance 100% Disease or condition metadata normalized. Organism normalized. Assay type normalized. Tissue metadata normalized.
  • comparison suitability 100% Tumor and normal sample groups detected. No excluded sample type flags detected. Matched tumor/normal design boosted for colorectal tumor-vs-normal tissue triage. Patient tissue or biopsy specimens boosted for tissue comparison triage. Colorectal, colon, rectal, or CRC disease context boosted for tumor-vs-normal tissue ranking.
  • metadata quality 100% Sample source clarity: All samples have source metadata and clear GSE/GSM accessions. Group clarity: Rule-based grouping found both case and control samples. Disease clarity: Disease or condition metadata normalized. Tissue clarity: Tissue metadata normalized. Treatment clarity: No unclear treatment split detected in the sample metadata. Replicate clarity: No pooled sample or technical replicate flags detected. Data availability clarity: Dataset-level processed or raw data availability is explicit.
  • data availability 100% Processed data available. Raw data available.
  • overall 100% Weighted score: 30% relevance, 30% comparison suitability, 25% metadata quality, 15% data availability.

Derived Classifications

  • Organism Homo sapiens Organism remains rule-derived: Homo sapiens.
  • Assay bulk RNA-seq Assay remains rule-derived: bulk RNA-seq.
  • Study design Tumor vs matched normal Study design remains rule-derived: Tumor vs matched normal.
  • Specimen/source Tissue Specimen/source remains rule-derived: Tissue.
  • Likely case group tumor sample 11 samples
  • Likely control group normal tissue 1 samples

Warnings

No ranking warnings are active.

Intent Interpretation

  • Active intent Patient tissue tumor-vs-normal Ranks human colorectal tissue or biopsy cohorts where tumor samples can be compared with normal controls.
  • Organism expectation Homo sapiens Dataset organism is interpreted as Homo sapiens.
  • Assay expectation bulk RNA-seq Dataset assay is interpreted as bulk RNA-seq.
  • Specimen assumption patient tissue or biopsy Derived specimen/source is Tissue.
  • Control-group assumption matched normal, adjacent normal, paired normal, healthy tissue control, or otherwise normal tissue control Derived study design is Tumor vs matched normal; likely groups are tumor sample vs normal tissue.
  • Score caps Applied when matching conditions are present non-human datasets stay below the primary recommendation band, missing colorectal/colon/rectal/CRC context stays below the primary recommendation band, biofluid and model-system datasets cannot reach Recommended by default, microarray and secondary assays are capped unless explicitly enabled, or small cohorts are capped below high-confidence recommendations
  • Warning rules 0 active warnings missing or unclear control group, unclear disease context, unclear tissue source, mixed sample types, model-system markers, secondary assay context, missing processed data, or small cohort size
  • Downgrade or exclusion reason Missing or unclear metadata: Treatment clarity: No unclear treatment split detected in the sample metadata. Derived from current-intent ranking reasons and warnings.

Applied Review Decisions

No active review decisions affect this ranking.

Ranking Facts

  • Supporting fact Tumor vs matched normal · Tissue · suitability 100%. Contributed to match or upgrade evidence.
  • Supporting fact Prioritized for patient tissue tumor-vs-normal triage. Contributed to match or upgrade evidence.
  • Supporting fact Prioritized assay: bulk RNA-seq is the active assay expectation. Contributed to match or upgrade evidence.
  • Supporting fact Prioritized disease context: colorectal, colon, rectal, or CRC metadata detected. Contributed to match or upgrade evidence.
  • Supporting fact Processed data is available for downstream review. Contributed to match or upgrade evidence.
  • Caution fact Missing or unclear metadata: Treatment clarity: No unclear treatment split detected in the sample metadata. Contributed to downgrade or manual-review evidence.

Manual Corrections

0 active

Source Evidence

4 sources

GEO

Primary source

Original dataset metadata, sample metadata, source links, and GEO data availability flags.

Dataset accession
GSE92914
Sample records
12 GSM samples
  • GEO has priority for original metadata under the Phase 3J source rules.
  • Processed data: available.
  • Raw data: available.
  • No external source conflict is present in the current runtime data.

recount3

Not imported

Planned trusted source for processed count availability.

GEO accession
GSE92914
  • No recount3 project identifier has been imported for this dataset.
  • Once imported, recount3 has priority for processed count availability.
  • The recount3 source filter excludes this dataset until that linkage exists.
No recount3 sync data available.

Expression Atlas

Not imported

Planned source for curated expression experiment links.

GEO accession
GSE92914
  • No Expression Atlas experiment identifier has been imported for this dataset.
  • Once imported, Expression Atlas has priority for curated expression experiment links.
  • The Expression Atlas source filter excludes this dataset until that linkage exists.
No Expression Atlas sync data available.

PubMed

Unavailable

Publication context when PubMed identifiers are already known.

GEO accession
GSE92914
  • No PubMed identifier is present in the current runtime metadata.
  • No live PubMed search is performed from the dataset detail page.
No publication identifier imported.

Dataset Feedback

0 stored

Original GEO Metadata

dataset_accession: GSE92914
dataset_title: RNA-Seq analysis of human colorectal cancer with liver metastasis
organism: Homo sapiens
assay_type: bulk RNA-seq
processed_data_available: true
raw_data_available: true
submission_date: 2016-12-26
last_update_date: 2019-05-15
organization_name: Shanghai Tenth People's Hospital
department: Not available
public_date: 2018-12-25
experiment_types: Expression profiling by high throughput sequencing
platforms: GPL18573 Illumina NextSeq 500 (Homo sapiens)
sub_series: Not available
bioproject: PRJNA358825
supplementary_files: TAR: GSE92914_RAW.tar
series_type: Series

Why It Matched

  • Tumor vs matched normal · Tissue · suitability 100%.
  • Prioritized for patient tissue tumor-vs-normal triage.
  • Prioritized assay: bulk RNA-seq is the active assay expectation.
  • Prioritized disease context: colorectal, colon, rectal, or CRC metadata detected.
  • Processed data is available for downstream review.

Why It May Not Be Suitable

  • Missing or unclear metadata: Treatment clarity: No unclear treatment split detected in the sample metadata.

Warnings

No warnings

Normalized Fields

56 fields
Field Value Source Origin Confidence Evidence Reason
assay_type bulk RNA-seq dataset GSE92914 Runtime Siftome inference GEO:dataset:GSE92914:6f23b6b0e3f0f2f62ea6ef06d21c209bf2c736c73434334464aa8c2cc70b6358 high confidence bulk rna-seq dataset_accession: GSE92914 dataset_title: RNA-Seq analysis of human colorectal cancer with liver metastasis organism: Homo sapiens assay_type: bulk RNA-seq processed_data_avail... keyword match keyword match: bulk rna-seq
disease colorectal cancer dataset GSE92914 Runtime Siftome inference GEO:dataset:GSE92914:6f23b6b0e3f0f2f62ea6ef06d21c209bf2c736c73434334464aa8c2cc70b6358 high confidence colorectal cancer dataset_accession: GSE92914 dataset_title: RNA-Seq analysis of human colorectal cancer with liver metastasis organism: Homo sapiens assay_type: bulk RNA-seq processed_data_avail... controlled vocabulary controlled vocabulary disease match: colorectal cancer
disease colorectal cancer sample GSM2440320 Runtime Siftome inference GEO:sample:GSM2440320:f596ed7138c094adb4bc6f4091bed72d58e8d1fc425335bb0c88727a5d6984a5 high confidence colorectal cancer sample_accession: GSM2440320 sample_title: liver metastasis 1_LM source_name: liver characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: liver metastasis; dis... controlled vocabulary controlled vocabulary disease match: colorectal cancer
disease colorectal cancer sample GSM2440321 Runtime Siftome inference GEO:sample:GSM2440321:dbd50c14ba5de5eeab8574bb92c472b2c248aefdc94014086073e2ea328a1fac high confidence colorectal cancer sample_accession: GSM2440321 sample_title: right colon primary tumor 1_MT source_name: right colon characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: right ... controlled vocabulary controlled vocabulary disease match: colorectal cancer
disease colorectal cancer sample GSM2440322 Runtime Siftome inference GEO:sample:GSM2440322:c0e100ec4c4d1340cb2bcd3e5d3522dc0b152494613de2b7bc4a73740d4b025e high confidence colorectal cancer sample_accession: GSM2440322 sample_title: right colon adjacent normal 1_PN source_name: right colon characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: righ... controlled vocabulary controlled vocabulary disease match: colorectal cancer
disease colorectal cancer sample GSM2440323 Runtime Siftome inference GEO:sample:GSM2440323:c16814d65476dc1c66802575428fcfde571da3a15841a25af8d761ca02981c06 high confidence colorectal cancer sample_accession: GSM2440323 sample_title: liver metastasis 2_LM source_name: liver characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: liver metastasis; disea... controlled vocabulary controlled vocabulary disease match: colorectal cancer
disease colorectal cancer sample GSM2440324 Runtime Siftome inference GEO:sample:GSM2440324:8014a173b8eb6091bb9177ab699b2adc684386b9c0aae9561cd84edfd6365ff7 high confidence colorectal cancer sample_accession: GSM2440324 sample_title: right colon primary tumor 2_MT source_name: right colon characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: right co... controlled vocabulary controlled vocabulary disease match: colorectal cancer
disease colorectal cancer sample GSM2440325 Runtime Siftome inference GEO:sample:GSM2440325:7a5706073d9d79962ab61ece35029aa867908f306de020f0766b0d6870f6ea8a high confidence colorectal cancer sample_accession: GSM2440325 sample_title: right colon primary tumor 2_PN source_name: right colon characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: right co... controlled vocabulary controlled vocabulary disease match: colorectal cancer
disease colorectal cancer sample GSM2440326 Runtime Siftome inference GEO:sample:GSM2440326:b1c94ae6c5bb91d77675dd00f2394251b96890be5e3baf76ab7fa5fde0a68f45 high confidence colorectal cancer sample_accession: GSM2440326 sample_title: liver metastasis 3_LM source_name: liver characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: liver metastasis; disea... controlled vocabulary controlled vocabulary disease match: colorectal cancer
disease colorectal cancer sample GSM2440327 Runtime Siftome inference GEO:sample:GSM2440327:a8294f040b459697a2a683447dad38a983e0f63ba5ea04a7a7e61bcb8141d88a high confidence colorectal cancer sample_accession: GSM2440327 sample_title: right colon primary tumor 3_MT source_name: right colon characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: right co... controlled vocabulary controlled vocabulary disease match: colorectal cancer
disease colorectal cancer sample GSM2440328 Runtime Siftome inference GEO:sample:GSM2440328:ccaba85ea696060fb89102fc755bb1536dadd1edf6947fc48a2e605dd1997232 high confidence colorectal cancer sample_accession: GSM2440328 sample_title: right colon primary tumor 3_PN source_name: right colon characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: right co... controlled vocabulary controlled vocabulary disease match: colorectal cancer
disease colorectal cancer sample GSM2440329 Runtime Siftome inference GEO:sample:GSM2440329:3f06d81a5cac08b4475d8b8ac4239ab97be8f94c32a7d67422e3d65771f7a31a high confidence colorectal cancer sample_accession: GSM2440329 sample_title: right colon primary tumor 4_NM source_name: right colon characteristics: gender: male; age (yr): 66; staging: T3N0M0; tissue: right co... controlled vocabulary controlled vocabulary disease match: colorectal cancer
disease colorectal cancer sample GSM2440330 Runtime Siftome inference GEO:sample:GSM2440330:6b5d121af1f49ee64e8e8de81b627edd7bc62e068a2deb30b00eb4f4455db8d7 high confidence colorectal cancer sample_accession: GSM2440330 sample_title: right colon primary tumor 5_NM source_name: right colon characteristics: gender: male; age (yr): 62; staging: T3N0M0; tissue: right co... controlled vocabulary controlled vocabulary disease match: colorectal cancer
disease colorectal cancer sample GSM2440331 Runtime Siftome inference GEO:sample:GSM2440331:811d73025e9d04b1b91070efbbbd9aba7669f68299ce8b2ce2e4e0c4c1f79995 high confidence colorectal cancer sample_accession: GSM2440331 sample_title: right colon primary tumor 6_NM source_name: right colon characteristics: gender: male; age (yr): 72; staging: T3N0M0; tissue: right co... controlled vocabulary controlled vocabulary disease match: colorectal cancer
normal_tissue_type adjacent normal sample GSM2440322 Runtime Siftome inference GEO:sample:GSM2440322:c0e100ec4c4d1340cb2bcd3e5d3522dc0b152494613de2b7bc4a73740d4b025e high confidence adjacent normal sample_accession: GSM2440322 sample_title: right colon adjacent normal 1_PN source_name: right colon characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: righ... controlled vocabulary controlled vocabulary normal tissue type match: adjacent normal
organism Homo sapiens dataset GSE92914 Runtime Siftome inference GEO:dataset:GSE92914:6f23b6b0e3f0f2f62ea6ef06d21c209bf2c736c73434334464aa8c2cc70b6358 high confidence homo sapiens dataset_accession: GSE92914 dataset_title: RNA-Seq analysis of human colorectal cancer with liver metastasis organism: Homo sapiens assay_type: bulk RNA-seq processed_data_avail... keyword match keyword match: homo sapiens
sample_type tumor sample sample GSM2440320 Runtime Siftome inference GEO:sample:GSM2440320:f596ed7138c094adb4bc6f4091bed72d58e8d1fc425335bb0c88727a5d6984a5 medium confidence metastasis sample_accession: GSM2440320 sample_title: liver metastasis 1_LM source_name: liver characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: liver metastasis; dis... controlled vocabulary controlled vocabulary sample type match: metastasis
sample_type tumor sample sample GSM2440321 Runtime Siftome inference GEO:sample:GSM2440321:dbd50c14ba5de5eeab8574bb92c472b2c248aefdc94014086073e2ea328a1fac low confidence tumor sample_accession: GSM2440321 sample_title: right colon primary tumor 1_MT source_name: right colon characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: right ... controlled vocabulary controlled vocabulary sample type match: tumor
sample_type normal tissue sample GSM2440322 Runtime Siftome inference GEO:sample:GSM2440322:c0e100ec4c4d1340cb2bcd3e5d3522dc0b152494613de2b7bc4a73740d4b025e high confidence adjacent normal sample_accession: GSM2440322 sample_title: right colon adjacent normal 1_PN source_name: right colon characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: righ... controlled vocabulary controlled vocabulary sample type match: adjacent normal
sample_type tumor sample sample GSM2440323 Runtime Siftome inference GEO:sample:GSM2440323:c16814d65476dc1c66802575428fcfde571da3a15841a25af8d761ca02981c06 medium confidence metastasis sample_accession: GSM2440323 sample_title: liver metastasis 2_LM source_name: liver characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: liver metastasis; disea... controlled vocabulary controlled vocabulary sample type match: metastasis
sample_type tumor sample sample GSM2440324 Runtime Siftome inference GEO:sample:GSM2440324:8014a173b8eb6091bb9177ab699b2adc684386b9c0aae9561cd84edfd6365ff7 low confidence tumor sample_accession: GSM2440324 sample_title: right colon primary tumor 2_MT source_name: right colon characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: right co... controlled vocabulary controlled vocabulary sample type match: tumor
sample_type tumor sample sample GSM2440325 Runtime Siftome inference GEO:sample:GSM2440325:7a5706073d9d79962ab61ece35029aa867908f306de020f0766b0d6870f6ea8a low confidence tumor sample_accession: GSM2440325 sample_title: right colon primary tumor 2_PN source_name: right colon characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: right co... controlled vocabulary controlled vocabulary sample type match: tumor
sample_type tumor sample sample GSM2440326 Runtime Siftome inference GEO:sample:GSM2440326:b1c94ae6c5bb91d77675dd00f2394251b96890be5e3baf76ab7fa5fde0a68f45 medium confidence metastasis sample_accession: GSM2440326 sample_title: liver metastasis 3_LM source_name: liver characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: liver metastasis; disea... controlled vocabulary controlled vocabulary sample type match: metastasis
sample_type tumor sample sample GSM2440327 Runtime Siftome inference GEO:sample:GSM2440327:a8294f040b459697a2a683447dad38a983e0f63ba5ea04a7a7e61bcb8141d88a low confidence tumor sample_accession: GSM2440327 sample_title: right colon primary tumor 3_MT source_name: right colon characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: right co... controlled vocabulary controlled vocabulary sample type match: tumor
sample_type tumor sample sample GSM2440328 Runtime Siftome inference GEO:sample:GSM2440328:ccaba85ea696060fb89102fc755bb1536dadd1edf6947fc48a2e605dd1997232 low confidence tumor sample_accession: GSM2440328 sample_title: right colon primary tumor 3_PN source_name: right colon characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: right co... controlled vocabulary controlled vocabulary sample type match: tumor
sample_type tumor sample sample GSM2440329 Runtime Siftome inference GEO:sample:GSM2440329:3f06d81a5cac08b4475d8b8ac4239ab97be8f94c32a7d67422e3d65771f7a31a low confidence tumor sample_accession: GSM2440329 sample_title: right colon primary tumor 4_NM source_name: right colon characteristics: gender: male; age (yr): 66; staging: T3N0M0; tissue: right co... controlled vocabulary controlled vocabulary sample type match: tumor
sample_type tumor sample sample GSM2440330 Runtime Siftome inference GEO:sample:GSM2440330:6b5d121af1f49ee64e8e8de81b627edd7bc62e068a2deb30b00eb4f4455db8d7 low confidence tumor sample_accession: GSM2440330 sample_title: right colon primary tumor 5_NM source_name: right colon characteristics: gender: male; age (yr): 62; staging: T3N0M0; tissue: right co... controlled vocabulary controlled vocabulary sample type match: tumor
sample_type tumor sample sample GSM2440331 Runtime Siftome inference GEO:sample:GSM2440331:811d73025e9d04b1b91070efbbbd9aba7669f68299ce8b2ce2e4e0c4c1f79995 low confidence tumor sample_accession: GSM2440331 sample_title: right colon primary tumor 6_NM source_name: right colon characteristics: gender: male; age (yr): 72; staging: T3N0M0; tissue: right co... controlled vocabulary controlled vocabulary sample type match: tumor
tissue colon dataset GSE92914 Runtime Siftome inference GEO:dataset:GSE92914:6f23b6b0e3f0f2f62ea6ef06d21c209bf2c736c73434334464aa8c2cc70b6358 medium confidence colorectal dataset_accession: GSE92914 dataset_title: RNA-Seq analysis of human colorectal cancer with liver metastasis organism: Homo sapiens assay_type: bulk RNA-seq processed_data_avail... controlled vocabulary controlled vocabulary tissue match: colorectal
tissue liver dataset GSE92914 Runtime Siftome inference GEO:dataset:GSE92914:6f23b6b0e3f0f2f62ea6ef06d21c209bf2c736c73434334464aa8c2cc70b6358 low confidence liver dataset_accession: GSE92914 dataset_title: RNA-Seq analysis of human colorectal cancer with liver metastasis organism: Homo sapiens assay_type: bulk RNA-seq processed_data_avail... controlled vocabulary controlled vocabulary tissue match: liver
tissue colon sample GSM2440320 Runtime Siftome inference GEO:sample:GSM2440320:f596ed7138c094adb4bc6f4091bed72d58e8d1fc425335bb0c88727a5d6984a5 medium confidence colorectal sample_accession: GSM2440320 sample_title: liver metastasis 1_LM source_name: liver characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: liver metastasis; dis... controlled vocabulary controlled vocabulary tissue match: colorectal
tissue liver sample GSM2440320 Runtime Siftome inference GEO:sample:GSM2440320:f596ed7138c094adb4bc6f4091bed72d58e8d1fc425335bb0c88727a5d6984a5 low confidence liver sample_accession: GSM2440320 sample_title: liver metastasis 1_LM source_name: liver characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: liver metastasis; dis... controlled vocabulary controlled vocabulary tissue match: liver
tissue colon sample GSM2440321 Runtime Siftome inference GEO:sample:GSM2440321:dbd50c14ba5de5eeab8574bb92c472b2c248aefdc94014086073e2ea328a1fac low confidence colon sample_accession: GSM2440321 sample_title: right colon primary tumor 1_MT source_name: right colon characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: right ... controlled vocabulary controlled vocabulary tissue match: colon
tissue colon sample GSM2440322 Runtime Siftome inference GEO:sample:GSM2440322:c0e100ec4c4d1340cb2bcd3e5d3522dc0b152494613de2b7bc4a73740d4b025e low confidence colon sample_accession: GSM2440322 sample_title: right colon adjacent normal 1_PN source_name: right colon characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: righ... controlled vocabulary controlled vocabulary tissue match: colon
tissue colon sample GSM2440323 Runtime Siftome inference GEO:sample:GSM2440323:c16814d65476dc1c66802575428fcfde571da3a15841a25af8d761ca02981c06 medium confidence colorectal sample_accession: GSM2440323 sample_title: liver metastasis 2_LM source_name: liver characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: liver metastasis; disea... controlled vocabulary controlled vocabulary tissue match: colorectal
tissue liver sample GSM2440323 Runtime Siftome inference GEO:sample:GSM2440323:c16814d65476dc1c66802575428fcfde571da3a15841a25af8d761ca02981c06 low confidence liver sample_accession: GSM2440323 sample_title: liver metastasis 2_LM source_name: liver characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: liver metastasis; disea... controlled vocabulary controlled vocabulary tissue match: liver
tissue colon sample GSM2440324 Runtime Siftome inference GEO:sample:GSM2440324:8014a173b8eb6091bb9177ab699b2adc684386b9c0aae9561cd84edfd6365ff7 low confidence colon sample_accession: GSM2440324 sample_title: right colon primary tumor 2_MT source_name: right colon characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: right co... controlled vocabulary controlled vocabulary tissue match: colon
tissue colon sample GSM2440325 Runtime Siftome inference GEO:sample:GSM2440325:7a5706073d9d79962ab61ece35029aa867908f306de020f0766b0d6870f6ea8a low confidence colon sample_accession: GSM2440325 sample_title: right colon primary tumor 2_PN source_name: right colon characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: right co... controlled vocabulary controlled vocabulary tissue match: colon
tissue colon sample GSM2440326 Runtime Siftome inference GEO:sample:GSM2440326:b1c94ae6c5bb91d77675dd00f2394251b96890be5e3baf76ab7fa5fde0a68f45 medium confidence colorectal sample_accession: GSM2440326 sample_title: liver metastasis 3_LM source_name: liver characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: liver metastasis; disea... controlled vocabulary controlled vocabulary tissue match: colorectal
tissue liver sample GSM2440326 Runtime Siftome inference GEO:sample:GSM2440326:b1c94ae6c5bb91d77675dd00f2394251b96890be5e3baf76ab7fa5fde0a68f45 low confidence liver sample_accession: GSM2440326 sample_title: liver metastasis 3_LM source_name: liver characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: liver metastasis; disea... controlled vocabulary controlled vocabulary tissue match: liver
tissue colon sample GSM2440327 Runtime Siftome inference GEO:sample:GSM2440327:a8294f040b459697a2a683447dad38a983e0f63ba5ea04a7a7e61bcb8141d88a low confidence colon sample_accession: GSM2440327 sample_title: right colon primary tumor 3_MT source_name: right colon characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: right co... controlled vocabulary controlled vocabulary tissue match: colon
tissue colon sample GSM2440328 Runtime Siftome inference GEO:sample:GSM2440328:ccaba85ea696060fb89102fc755bb1536dadd1edf6947fc48a2e605dd1997232 low confidence colon sample_accession: GSM2440328 sample_title: right colon primary tumor 3_PN source_name: right colon characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: right co... controlled vocabulary controlled vocabulary tissue match: colon
tissue colon sample GSM2440329 Runtime Siftome inference GEO:sample:GSM2440329:3f06d81a5cac08b4475d8b8ac4239ab97be8f94c32a7d67422e3d65771f7a31a low confidence colon sample_accession: GSM2440329 sample_title: right colon primary tumor 4_NM source_name: right colon characteristics: gender: male; age (yr): 66; staging: T3N0M0; tissue: right co... controlled vocabulary controlled vocabulary tissue match: colon
tissue colon sample GSM2440330 Runtime Siftome inference GEO:sample:GSM2440330:6b5d121af1f49ee64e8e8de81b627edd7bc62e068a2deb30b00eb4f4455db8d7 low confidence colon sample_accession: GSM2440330 sample_title: right colon primary tumor 5_NM source_name: right colon characteristics: gender: male; age (yr): 62; staging: T3N0M0; tissue: right co... controlled vocabulary controlled vocabulary tissue match: colon
tissue colon sample GSM2440331 Runtime Siftome inference GEO:sample:GSM2440331:811d73025e9d04b1b91070efbbbd9aba7669f68299ce8b2ce2e4e0c4c1f79995 low confidence colon sample_accession: GSM2440331 sample_title: right colon primary tumor 6_NM source_name: right colon characteristics: gender: male; age (yr): 72; staging: T3N0M0; tissue: right co... controlled vocabulary controlled vocabulary tissue match: colon
tumor_type metastatic tumor sample GSM2440320 Runtime Siftome inference GEO:sample:GSM2440320:f596ed7138c094adb4bc6f4091bed72d58e8d1fc425335bb0c88727a5d6984a5 medium confidence metastasis sample_accession: GSM2440320 sample_title: liver metastasis 1_LM source_name: liver characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: liver metastasis; dis... controlled vocabulary controlled vocabulary tumor type match: metastasis
tumor_type primary tumor sample GSM2440321 Runtime Siftome inference GEO:sample:GSM2440321:dbd50c14ba5de5eeab8574bb92c472b2c248aefdc94014086073e2ea328a1fac high confidence primary tumor sample_accession: GSM2440321 sample_title: right colon primary tumor 1_MT source_name: right colon characteristics: gender: female; age (yr): 62; staging: T3N2M1; tissue: right ... controlled vocabulary controlled vocabulary tumor type match: primary tumor
tumor_type metastatic tumor sample GSM2440323 Runtime Siftome inference GEO:sample:GSM2440323:c16814d65476dc1c66802575428fcfde571da3a15841a25af8d761ca02981c06 medium confidence metastasis sample_accession: GSM2440323 sample_title: liver metastasis 2_LM source_name: liver characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: liver metastasis; disea... controlled vocabulary controlled vocabulary tumor type match: metastasis
tumor_type primary tumor sample GSM2440324 Runtime Siftome inference GEO:sample:GSM2440324:8014a173b8eb6091bb9177ab699b2adc684386b9c0aae9561cd84edfd6365ff7 high confidence primary tumor sample_accession: GSM2440324 sample_title: right colon primary tumor 2_MT source_name: right colon characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: right co... controlled vocabulary controlled vocabulary tumor type match: primary tumor
tumor_type primary tumor sample GSM2440325 Runtime Siftome inference GEO:sample:GSM2440325:7a5706073d9d79962ab61ece35029aa867908f306de020f0766b0d6870f6ea8a high confidence primary tumor sample_accession: GSM2440325 sample_title: right colon primary tumor 2_PN source_name: right colon characteristics: gender: male; age (yr): 58; staging: T3N2M1; tissue: right co... controlled vocabulary controlled vocabulary tumor type match: primary tumor
tumor_type metastatic tumor sample GSM2440326 Runtime Siftome inference GEO:sample:GSM2440326:b1c94ae6c5bb91d77675dd00f2394251b96890be5e3baf76ab7fa5fde0a68f45 medium confidence metastasis sample_accession: GSM2440326 sample_title: liver metastasis 3_LM source_name: liver characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: liver metastasis; disea... controlled vocabulary controlled vocabulary tumor type match: metastasis
tumor_type primary tumor sample GSM2440327 Runtime Siftome inference GEO:sample:GSM2440327:a8294f040b459697a2a683447dad38a983e0f63ba5ea04a7a7e61bcb8141d88a high confidence primary tumor sample_accession: GSM2440327 sample_title: right colon primary tumor 3_MT source_name: right colon characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: right co... controlled vocabulary controlled vocabulary tumor type match: primary tumor
tumor_type primary tumor sample GSM2440328 Runtime Siftome inference GEO:sample:GSM2440328:ccaba85ea696060fb89102fc755bb1536dadd1edf6947fc48a2e605dd1997232 high confidence primary tumor sample_accession: GSM2440328 sample_title: right colon primary tumor 3_PN source_name: right colon characteristics: gender: male; age (yr): 57; staging: T3N1M1; tissue: right co... controlled vocabulary controlled vocabulary tumor type match: primary tumor
tumor_type primary tumor sample GSM2440329 Runtime Siftome inference GEO:sample:GSM2440329:3f06d81a5cac08b4475d8b8ac4239ab97be8f94c32a7d67422e3d65771f7a31a high confidence primary tumor sample_accession: GSM2440329 sample_title: right colon primary tumor 4_NM source_name: right colon characteristics: gender: male; age (yr): 66; staging: T3N0M0; tissue: right co... controlled vocabulary controlled vocabulary tumor type match: primary tumor
tumor_type primary tumor sample GSM2440330 Runtime Siftome inference GEO:sample:GSM2440330:6b5d121af1f49ee64e8e8de81b627edd7bc62e068a2deb30b00eb4f4455db8d7 high confidence primary tumor sample_accession: GSM2440330 sample_title: right colon primary tumor 5_NM source_name: right colon characteristics: gender: male; age (yr): 62; staging: T3N0M0; tissue: right co... controlled vocabulary controlled vocabulary tumor type match: primary tumor
tumor_type primary tumor sample GSM2440331 Runtime Siftome inference GEO:sample:GSM2440331:811d73025e9d04b1b91070efbbbd9aba7669f68299ce8b2ce2e4e0c4c1f79995 high confidence primary tumor sample_accession: GSM2440331 sample_title: right colon primary tumor 6_NM source_name: right colon characteristics: gender: male; age (yr): 72; staging: T3N0M0; tissue: right co... controlled vocabulary controlled vocabulary tumor type match: primary tumor

Sample Group Preview

Possible case samples

Samples currently treated as the comparison case group.

11
  • GSM2440320 liver metastasis 1_LM tumor sample Case marker detected. liver gender: female; age (yr): 62; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient
  • GSM2440321 right colon primary tumor 1_MT tumor sample Case marker detected. right colon gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
  • GSM2440323 liver metastasis 2_LM tumor sample Case marker detected. liver gender: male; age (yr): 58; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient
  • GSM2440324 right colon primary tumor 2_MT tumor sample Case marker detected. right colon gender: male; age (yr): 58; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
  • GSM2440325 right colon primary tumor 2_PN tumor sample Case marker detected. right colon gender: male; age (yr): 58; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
  • GSM2440326 liver metastasis 3_LM tumor sample Case marker detected. liver gender: male; age (yr): 57; staging: T3N1M1; tissue: liver metastasis; disease state: colorectal cancer patient
  • GSM2440327 right colon primary tumor 3_MT tumor sample Case marker detected. right colon gender: male; age (yr): 57; staging: T3N1M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
  • GSM2440328 right colon primary tumor 3_PN tumor sample Case marker detected. right colon gender: male; age (yr): 57; staging: T3N1M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
  • GSM2440329 right colon primary tumor 4_NM tumor sample Case marker detected. right colon gender: male; age (yr): 66; staging: T3N0M0; tissue: right colon primary tumor; disease state: colorectal cancer patient
  • GSM2440330 right colon primary tumor 5_NM tumor sample Case marker detected. right colon gender: male; age (yr): 62; staging: T3N0M0; tissue: right colon primary tumor; disease state: colorectal cancer patient
  • GSM2440331 right colon primary tumor 6_NM tumor sample Case marker detected. right colon gender: male; age (yr): 72; staging: T3N0M0; tissue: right colon primary tumor; disease state: colorectal cancer patient

Possible control samples

Samples currently treated as controls or baseline.

1
  • GSM2440322 right colon adjacent normal 1_PN normal tissue Control marker detected. right colon gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon adjacent normal; disease state: colorectal cancer patient

Unassigned samples

Samples with no explicit case or control marker.

0

No samples

Excluded samples

Samples excluded from grouping by hard exclusion rules.

0

No samples

Ambiguous samples

Samples that need manual review before trusting grouping.

0

No samples

Metadata Quality Components

Detected Sample Groups

tumor sample

11 samples
  • GSM2440320 liver metastasis 1_LM liver gender: female; age (yr): 62; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient
  • GSM2440321 right colon primary tumor 1_MT right colon gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
  • GSM2440323 liver metastasis 2_LM liver gender: male; age (yr): 58; staging: T3N2M1; tissue: liver metastasis; disease state: colorectal cancer patient
  • GSM2440324 right colon primary tumor 2_MT right colon gender: male; age (yr): 58; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
  • GSM2440325 right colon primary tumor 2_PN right colon gender: male; age (yr): 58; staging: T3N2M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
  • GSM2440326 liver metastasis 3_LM liver gender: male; age (yr): 57; staging: T3N1M1; tissue: liver metastasis; disease state: colorectal cancer patient
  • GSM2440327 right colon primary tumor 3_MT right colon gender: male; age (yr): 57; staging: T3N1M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
  • GSM2440328 right colon primary tumor 3_PN right colon gender: male; age (yr): 57; staging: T3N1M1; tissue: right colon primary tumor; disease state: colorectal cancer patient
  • GSM2440329 right colon primary tumor 4_NM right colon gender: male; age (yr): 66; staging: T3N0M0; tissue: right colon primary tumor; disease state: colorectal cancer patient
  • GSM2440330 right colon primary tumor 5_NM right colon gender: male; age (yr): 62; staging: T3N0M0; tissue: right colon primary tumor; disease state: colorectal cancer patient
  • GSM2440331 right colon primary tumor 6_NM right colon gender: male; age (yr): 72; staging: T3N0M0; tissue: right colon primary tumor; disease state: colorectal cancer patient

normal tissue

1 sample
  • GSM2440322 right colon adjacent normal 1_PN right colon gender: female; age (yr): 62; staging: T3N2M1; tissue: right colon adjacent normal; disease state: colorectal cancer patient

Score Breakdown

100%

relevance

  • Disease or condition metadata normalized.
  • Organism normalized.
  • Assay type normalized.
  • Tissue metadata normalized.
100%

comparison suitability

  • Tumor and normal sample groups detected.
  • No excluded sample type flags detected.
  • Matched tumor/normal design boosted for colorectal tumor-vs-normal tissue triage.
  • Patient tissue or biopsy specimens boosted for tissue comparison triage.
  • Colorectal, colon, rectal, or CRC disease context boosted for tumor-vs-normal tissue ranking.
100%

metadata quality

  • Sample source clarity: All samples have source metadata and clear GSE/GSM accessions.
  • Group clarity: Rule-based grouping found both case and control samples.
  • Disease clarity: Disease or condition metadata normalized.
  • Tissue clarity: Tissue metadata normalized.
  • Treatment clarity: No unclear treatment split detected in the sample metadata.
  • Replicate clarity: No pooled sample or technical replicate flags detected.
  • Data availability clarity: Dataset-level processed or raw data availability is explicit.
100%

data availability

  • Processed data available.
  • Raw data available.
100%

overall

  • Weighted score: 30% relevance, 30% comparison suitability, 25% metadata quality, 15% data availability.

Sample Links

12 samples

Review Audit Trail

0 decisions

No review decisions have been stored for this dataset.